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Search Results for " pim-1/2 kinase inhibitor 1 "

9

Compounds

Cat No. Product Name Synonyms Targets
T9229 Pim-1/2 kinase inhibitor 1 Pim
Pim-1/2 Kinase Inhibitor 1, an orally active inhibitor, impedes the action of Pim kinases by preventing their ability to phosphorylate peptides. It particularly inhibits the phosphorylation of 4E-BP1 and p27 Kip1 by Pim ...
T62001 Pim-1 kinase inhibitor 2
Pim-1 kinase inhibitor 2 (Compound 13), a potent inhibitor of Pim-1 kinase, has the potential for cancer research due to its ability to induce apoptosis [1].
T1834 CX-6258 CX 6258 Pim
CX-6258 is an orally valid Pim 1/2/3 kinase(IC50=5 nM/25 nM/16 nM) inhibitor. It has good biological activity and kinase specificity.
T6148 CX-6258 hydrochloride CX-6258 HCl,Pim-Kinase Inhibitor X Pim
CX-6258 hydrochloride (Pim-Kinase Inhibitor X) is an effective, orally efficacious Pim1/2/3 kinase inhibitor (IC50: 5/25/16 nM).
T3058 (Z)-SMI-4a TCS PIM-1 4a,SMI-4a Pim
(Z)-SMI-4a (TCS PIM-1 4a) is a selective ATP-competitive Pim-1 kinase inhibitor with an IC50 of 21 nM.
T3078 SGI-1776 SGI-1776 free base,Pim-Kinase Inhibitor IX Apoptosis , FLT , Pim , Autophagy
SGI-1776 (Pim-Kinase Inhibitor IX) has been used in trials studying the treatment of Prostate Cancer, Non-Hodgkins Lymphoma, and Relapsed/Refractory Leukemias.
T3989 SMI-16a PIM1/2 Kinase Inhibitor VI Pim
SMI-16a (PIM1/2 Kinase Inhibitor VI) , a cell-permeable thiazolidinedione compound, acts as an effective, ATP-competitive inhibitor against Pim-1/2 kinases (IC50: 150/20 nM) while exhibiting little or no activity against...
T23158 PIM-1 Inhibitor 2 Others
PIM-1 Inhibitor 2 is an effective Pim-1 kinase inhibitor (Ki = 91 nM).
T63589 CX-6258 hydrochloride hydrate
CX-6258 hydrochloride hydrate is a potent and selective inhibitor of pan-Pim kinase that acts on Pim-1 (IC50: 5 nM), Pim-2 (IC50: 25 nM) and Pim-3 (IC50: 16 nM).
TargetMol